Radius Health, Inc

AVI BioPharma is a biopharmaceutical company that develops drugs to treat life-threatening diseases using its patented third generation antisense technology. It has completed clinical trials with its NeuGene antisense drugs in more than 300 subjects, addressing cardiovascular restenosis, infectious diseases, cancer, polycystic kidney disease and drug metabolism. Its most advanced cardiovascular program is for restenosis, where it has completed Phase II trials, evaluating its drug, Resten-NG. AVI BioPharma is also in a Phase II clinical trial with a drug for Hepatitis C infection and its influenza A drug candidate has been confirmed to have efficacy against avian influenza H5N1 in preclinical studies. AVI BioPharma maintains a location in Portland, Ore.

Vertex Pharmaceuticals Incorporated is a global biotechnology company engaged in the discovery and development of breakthrough small molecule drugs for serious diseases. The company commercializes its products independently and in collaboration with major pharmaceutical companies. Vertex s product line includes drugs for viral diseases, inflammation, autoimmune diseases and cancer. Vertex is developing treatments for cancer, HIV and AIDS and pain through collaborations with some of the leading pharmaceutical companies. The company has collaborations with Cystic Fibrosis Foundation Therapeutics, GlaxoSmithKline, Kissei Pharmaceutical, Merck & Co., Mitsubishi Pharma Corporation and Novartis Pharma. Vertex co-promotes the HIV and AIDS protease inhibitor, Lexiva, with GlaxoSmithKline. Vertex Pharmaceuticals Incorporated is located in Cambridge, Mass.

Metabolic Solutions provides a mass spectrometry analytical service to assist physicians, pharmaceutical developers and biomedical researchers in using isotope tracers to answer their questions about metabolism, nutrition and the presence of disease. The company is an independent, CLIA-certified clinical laboratory that provides kits and analysis for the Urea Breath Test to detect H. pylori infection, as well as the Hydrogen Breath Test for determining lactose intolerance. Metabolic Solutions laboratory is licensed to provide clinical lab services in all 50 states. All specimens are processed and results are reported within 24 hours of receipt. Metabolic Solutions also helps researchers to use stable and radioactive isotope tracers as biomarkers to study human and animal metabolic processes. The company s complete services include study protocol consultation, building custom test kits and a responsive analytical service compliant with current FDA Good Laboratory Practices. Since 1990, more than 500 researchers worldwide have relied on Metabolic Solutions for stable isotope measurements. The company is based in Nashua, N.H.