M Brothers at Mayo

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4500 San Pablo Rd S
Jacksonville, FL 32224
+1 (904) 953-0409
https://medurebrothers.com

MBrothers, located within the Mayo Building Atrium at Jacksonville's Mayo Clinic, honors a rich tradition of excellence that dates back 150 years with the Mayo Brothers. Led by chef-entrepreneurs Matthew and David Medure, the restaurant is renowned for its innovative cuisine, beautiful presentation, and a stylish yet comfortable ambiance, all underscored by a genuine love for serving guests.

In addition to its full-service dining experience, MBrothers offers unique monthly tasting menus inspired by different regions of the world, inviting guests to embark on culinary adventures. The establishment is complemented by Zest, a gourmet grab-and-go market that provides convenient meal options, ensuring a delightful dining experience for all visitors.

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4.564 reviews
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Michelle T.
7/10/2025

Can't believe I have not been to this hidden jewel , but then I make my appointments early morning at Mayo. Went for lunch and was so impressed with the dinning room. Full tablecloths that just...

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Francis S.
5/21/2025

I've dined here more times than I've checked in -- often for work-related events, casual lunches, and even a graduation reception. And while I always want to love it (especially given its...

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Jasmine F.
10/18/2024

I stopped by during a visit to Mayo today. Having eaten at Medure and Midtown Table, I am very familiar with the quality of the Medure Brothers brand. The restaurant was upscale for a hospital. It...

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Kate C.
10/3/2024

Really good food in a surprising place! Met friends for late lunch after one had an appointment at this absolute little treasure I had the burger and wow! It was thick, juicy, flavorful and...

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Kris F.
4/15/2025

Nice Madure Brothers restaurant tucked away inside the Mayo Clinic hospital Florida! Beautiful decor, and nice ambience. Professional servers will delight you with wonderful selections from the...

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