Tecolote Research

Based at NASA's Johnson Space Center in Houston, Texas, Odyssey Space Research, LLC provides technical expertise, spacecraft engineering and research services for the aerospace industry. It offers engineering research and analysis services in the core domain of Guidance, Navigation and Control (GN&C) design, analysis, integration, evaluation and testing. Some of Odyssey Space Research, LLC's completed projects include Hubble Space Telescope Robotic Vehicle (HRV), Mini Autonomous Extravehicular Robotic Camera (Mini AERCam) and Orbital Space Plane (OSP).

Nanospectra Biosciences is a private company founded in 2002. Nanospectra has an exclusive license from Rice University to eleven issued US patents related to nanoshells and related commercial uses of these and other nanoparticles. While there are numerous therapeutic, diagnostic, and industrial commercial applications, Nanospectra is focused on the development of AuroLase Therapy utilizing AuroShell Particles ( also referred to as nanoshells ) for the precise, particle-based thermal ablation of solid tumors. Nanospectra commenced formal operations in 2002 to commercialize these applications. Nanospectra has an open Investigational Device Exemption ( IDE ) wtih the U.S. FDA to evaluate the safety and efficacy of AuroLase Therapy for the treatment of refractory or recurrent head and neck cancers. The use of AuroLase Therapy in other cancer types is under development. Nanoshells were developed in the laboratories of Naomi Halas, PhD, and Stanley C. Moore, Professor in Electrical and Computer Engineering and Professor of physics, chemistry, and Biomedical engineering at Rice University, in the 1990's. In collaboration with Jennifer West, PhD, and Isabel C. Cameron, Professor and Chair of Bioengineering of Rice University, a series of life science applications were envisioned which led to the formation of Nanospectra. Drs. Halas and West were named Inventors of the Year by the Texas Bar Assocation for one of their numerous patents licensed to Nanospectra. In addition to the work of our founding scientists, other leading scientists contributed to the development of our technology and product applications. Several of the collaborators who have made significant contributions to our success include: Rinat Esenaliev, PhD., Professor, Director of Laboratory for Optical Sensing and Monitoring, Center for Biomedical Engineering, UTMB Cancer Center, Department of Neuroscience and Cell Biology, and Department of Anesthesiology, University of Texas Medical Branch. Dr. Esenaliev performed pioneering work in the use of electromagnetic radiation and particle-assisted therapies for the treatment of cancer. Nanospectra has a license to Dr. Eseanliev's early patent in this area. John Hazle, PhD, FAAPM, Professor, Department of Imaging Physics, Division of Diagnostic Imaging, The University of Texas M. D. Anderson Cancer Center. Dr. Hazle collaborated with our founders and performed the initial thermal profiling in vivo studies of our technology, and he has led the development of several imaged guided and feedback applications of our therapy. We have been awarded peer-reviewed federal grants and awards exceeding $6 million to develop AuroShell particles for the diagnosis and treatment of cancer and for other diagnostic and commercial applications. Additional funding in excess of $6 million has been raised from angel investors, private investment funds, and the Texas State Emerging Technology Fund.