Pepe's Cafe

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[1301 - 1551] Sheffield Rd
Ozona, TX 76943

Pepe's Cafe, the oldest eatery in the Florida Keys, has been delighting customers since 1909 when Teddy Roosevelt was President. Celebrated for its vibrant atmosphere and award-winning cocktails, this historic steakhouse has been recognized for serving the Best Mojito and Best Margarita in Key West according to the 2024 BUBBAS Key West People's Choice Awards.

With a commitment to freshness, Pepe's offers made-to-order oysters, fresh-squeezed juices, and homemade dressings, all contributing to a distinctive dining experience. Not only is it a culinary gem, but Pepe's Cafe also welcomes pets, making it a must-visit destination for everyone exploring Key West.

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Reviews

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4.0141 reviews
Photo of Nick M.
Nick M.
8/11/2025

If you're not from Texas and you have ever wondered what Tex Mex is this is the place for you... It is an amazing value and freshly prepared tasty food by some of the friendliest folks you will...

Photo of Mike R.
Mike R.
7/24/2025

Stopped in on my way to Alpine. We were a group of five. The special was enchiladas, chicken, beef or cheese. SIL got the burrito, wife crispy tacos & I had steak tacos. We all agreed food was...

Photo of andrew g.
andrew g.
1/28/2025

Where the 10 and the 163 meet there is a place called Ozona. You might pass through here on a roadtrip and while at the gas station you might spot Pepe's. Go ahead and give it a try. I recommend...

Photo of Dorina S.
Dorina S.
6/26/2025

Stopped in on the way to San Antonio. Great burgers and delicious shrimp tacos! Very cute place and excellent service!

Photo of Dalv C.
Dalv C.
7/19/2024

Very colorful place. Many beautiful hand-pained and hand-drawn portraits. This place in in the small scale. A dozen table or so. If traveling West Bound or East Bound on Route 10 in Beautiful...

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