William Purvis Lancaster, MD - MUSC Health Surgical Oncology at Ashley River Tower

Dr. Michelle Hudspeth is a 1999 graduate of the MUSC College of Medicine and completed her residency, chief residency, and fellowship at the Johns Hopkins Hospital and the National Cancer Institute. She is the division chief for pediatric hematology/oncology and is the director of the pediatric blood and marrow transplant program and the quality director for the combined adult and pediatric blood and marrow transplant program. Her main clinical focus is transplantation, including haploidentical, related and unrelated allogeneic, cord blood, and autologous donor sources. She is the institutional principal investigator for Pediatric Blood and Marrow Transplant Consortium trials. She is a member of the Pediatric Blood and Marrow Transplant Consortium GVHD committee and supportive care committee. She also serves on several working committees (GVHD, pediatric cancer, immune deficiencies/inborn errors of metabolism) for the Center for International Blood and Marrow Transplant Research. Her clinical research includes multiple aspects of transplantation, including a clinical trial incorporating pravastatin for matched related donor transplants for sickle cell disease.

Dr. Charles Greenberg practices medicine in the area of nonmalignant blood disorders. He provides consultative advice regarding the diagnosis and treatment of bleeding, thrombosis, and disorders of blood cells. Dr. Greenberg conducts translational research regarding new diagnostic tests for management of bleeding and thrombotic disorders. Working in collaborations within the MUSC health care system he assists in management of blood, blood products, and the cost-effective management on nonmalignant blood disorders. Clinical research on the use new approaches to manage bleeding and thrombosis continue as part of national and international groups targeting life-threatening blood disorders. Dr. Greenberg's basic research is in the area of transglutaminase structure and function and he has published in the area of Factor XIII and tissue transglutaminase biology related to hemostasis, thrombosis, wound healing, angiogenesis, and tumor growth.

Dr. Jacqueline Kraveka is an associate professor of pediatrics and a pediatric hematologist-oncologist at the Medical University of South Carolina (MUSC) in Charleston, South Carolina. She was born in Velasco, Cuba and immigrated to the United States when she was four years of age. Dr. Kraveka received her undergraduate degree from Columbia University in 1989 and her medical degree from Nova Southeastern University College of Osteopathic Medicine in 1994. She completed her residency in pediatrics at Miami Children's Hospital in 1997 and fellowship in pediatric hematology oncology at the Medical University of South Carolina in 2000.Since 2000, she has been on staff at the Medical University of South Carolina Children's Hospital.Dr. Kraveka's clinical practice is focused on pediatric oncology. Her clinical interests include neuroblastoma, pediatric sarcomas, pediatric precision medicine, and clinical trial development. She is actively involved in clinical pediatric research in the Children's Oncology Group (COG) and Beat Childhood Cancer (BCC) consortia and serves as the institutional principal investigator for these consortia. As such,Dr. Kraveka is responsible for the conduct of over 50 Phase I, II, and III clinical trials for pediatric oncology patients at MUSC. She has been involved in the development of over 10 pediatric clinical trials for children with cancer.Dr. Kraveka serves on the COG Neuroblastoma and Diversity and Health Disparities Committees and is a member of the BCC Executive and Scientific Committees. She has been honored as a &"Top Doctor&" and "Exceptional Women in Medicine&" by Castle Connolly. She was selected as a &"Health Care Hero&" by the Charleston Regional Business Journal. Dr. Kraveka is also very involved in translational and bench research and has the only research laboratory in South Carolina dedicated to pediatric cancer.Dr. Kraveka's current research focuses on sphingolipid and retinoid mediated therapies in pediatric cancers and the function and regulation of the enzyme dihydroceramide desaturase (DEGS-1) in pediatric cancer. The long-term goals of her research are to develop more effective treatments for children with cancer.