The Litter Box

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46 Old Wild Horse Rd
Hilton Head Island, SC 29926

The Hilton Head Humane Association is dedicated to enhancing the lives of homeless dogs and cats while actively working to reduce the number of animals that are reproduced or relinquished. Over the past year, the organization has provided care for more than 10,000 abandoned, injured, and abused animals, as well as feral cats.

In addition to its adoption services, the association also offers a spay and neuter clinic and runs a thrift store that supports its mission. With a commitment to improving animal welfare, the Hilton Head Humane Association stands as a vital resource in the community for both pets and their potential adoptive families.

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Reviews

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4.538 reviews
Photo of Trish P.
Trish P.
5/10/2025

I've been here a few times and always find something to fall in love with. Make sure to check them out

Photo of Sonya P.
Sonya P.
12/30/2024

Best thrift store on the island! Organized, friendly staff and good prices. We will return.

Photo of Amanda S.
Amanda S.
10/1/2024

Very clean and organized nicely. Lots of room between clothing racks. Prices are reasonable and the money goes to a great cause.

Marilyn B.
10/2/2024

Very friendly people! Helpful and courteous! Neat and clean! Even my husband enjoyed shopping there.

Gayle M.
3/10/2025

Great service. The staff is friendly and helpful. The store is well organized. They have a wide variety all resonably priced.

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