Six & Twenty Distillery

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556 Perry Ave Ste B103
Greenville, SC 29611
Six and Twenty Distillery is a grain to glass maker of premium spirits. We rely on locally-sourced materials for our products, and pride ourselves in being South Carolina's finest distillery. We're open to the public and encourage folks to stop in and see for themselves what makes craft spirits truly unique. Our gift shop allows for on-site purchases, samples and a chance to meet our craftsmen. Our new space also features a cocktail bar where you can experience all that our spirits have to offer. Cheers!

Reviews

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5.060 reviews
Photo of Smythe R.
Smythe R.
6/15/2025

Stopped in at their new digs (well, they've been here for 4 years, but I've not visited here since they moved. There was this whole pandemic/lockdown, see, and I kinda didn't travel...) and now...

Jonathan L.
9/6/2025

We booked the distillery tour and tasting. We arrived at 4:05, and were kindly greeted by Matt with a cocktail of our choice. It was my wife's birthday, and they made every effort to make it...

Photo of Jerry T.
Jerry T.
5/3/2024

We discovered this place right down the street from an AirB&B we rented in Greenville. We came in to do a tasting because I saw that they had a 5 grain bourbon. We were seated right away by our...

Photo of Madison M.
Madison M.
2/3/2024

Six and twenty is such a little local gem. LOVE using their Carolina cream for espresso Martinis and cocktails at home. Their cocktails at their location are awesome and the bar staff is great....

Photo of Jade W.
Jade W.
1/30/2023

I highly recommend it if you are in the area and looking for something fun to do. The tours are at certain times; 2:00 and 4:00 p.m. are two of the tour times. You can book online and pay onsite...

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