Alphalab

Vivasc Therapeutics Inc., based in Pittsburgh, PA, specializes in innovative drug delivery systems focused on reversing the effects of heart failure and treating atrial fibrillation. Utilizing their proprietary Cardiac Targeting Peptide, they aim to deliver therapeutic agents specifically to cardiomyocytes, addressing underlying cellular dysfunction rather than merely alleviating symptoms associated with heart diseases. Founded in 2020, the company has engaged in several STTR Phase I projects, demonstrating significant advancements in delivery methods for treatment options like miRNA and amiodarone, designed to target heart tissues with precision. Their research holds promise for improving patient outcomes by mitigating adverse effects commonly related to current heart failure and arrhythmia treatments. Generated from the website

The Lee Oesterreich Lab, led by Dr. Adrian Lee and Dr. Steffi Oesterreich, is dedicated to studying the molecular basis of breast cancer development and resistance to therapy. Their research aims to improve precision medicine and outcomes for breast cancer patients by utilizing a systems biology approach, incorporating single cell and bulk sequencing, computational methods, and biological models to identify and validate new drivers and therapeutic targets. With a focus on understanding invasive lobular cancer (ILC), the second most common but understudied histological subtype of breast cancer, the lab also investigates mechanisms of resistance to endocrine therapy and new approaches to blocking breast cancer metastasis. They collaborate with a large network of clinicians and nurses to analyze human specimens and large biomedical and genomic datasets, including electronic health record data. The lab maintains a strong training environment and prioritizes a healthy lab environment to ensure high productivity and rigor.Generated from the website

The Fazeli Lab, part of the University of Pittsburgh's Division of Endocrinology and Metabolism, is dedicated to advancing research in transdermal estrogen therapy. Situated within the Translational Research Center at UPMC Montefiore, the lab focuses on innovative studies aimed at understanding the effects and applications of estrogen treatments. With a commitment to excellence in medical research, the Fazeli Lab collaborates with experienced professionals to contribute valuable insights to the field. Their ongoing projects highlight the lab's dedication to improving health outcomes through cutting-edge scientific inquiry. Generated from the website