Santo Domingo Taqueria

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5447 NE 42nd Ave
Portland, OR 97218

Santo Domingo Taqueria, nestled in NE Portland's Cully neighborhood, invites patrons to savor homemade dishes brimming with the authentic flavors of Oaxaca's Mixteca Region. Using locally sourced ingredients, they offer a tantalizing array of Mexican delights complemented by the allure of authentic mezcal from Oaxaca.

With a mission to share their cherished recipes from Oaxaca's Mixtec region, Santo Domingo Taqueria prides itself on serving fresh, locally grown fare that encapsulates the essence of traditional Mexican cuisine. Each dish reflects a labor of love, bringing a taste of Mexico to the vibrant culinary scene of Portland.

From the ever-popular Tlayuda to the mouthwatering shredded beef enchiladas, Santo Domingo Taqueria has garnered acclaim from patrons like Rourke S and Jessica S for its generous portions, scrumptious flavors, and warm service. Experience a slice of Mexico in Portland as you indulge in their delectable offerings, all crafted with a commitment to authenticity and quality.

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Reviews

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4.0184 reviews
Photo of Brian S.
Brian S.
7/2/2025

I've been eating here for 25+ years though I don't live in the neighborhood anymore so don't get by too often, though it is so good I make a point of stopping when I'm traveling to and from the...

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Ariel W.
5/9/2025

Decent tacos. The pastor was on point. They have some covered picnic tables out front which is nice if you want a place you can bring your dog.

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Heather R.
6/3/2025

I visited Santo Domingo Taqueria for dinner. It was easy to order at the counter and the service was friendly. The patio was nice and there was some good indoor seating as well. The horchata was...

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Arnab D.
11/20/2024

Ordered fajita burrito and Oregon burrito for breakfast/brunch and was not disappointed at all. The flavors, taste matched the expectations and so did the side of hot sauce. I'll try out the...

Photo of Patrick s.
Patrick s.
6/7/2024

On the hunt for my favorite burrito. And unfortunately this was a miss. Walking in at lunch time on a Thursday this seemed promising. And don't get me wrong it was good. But three star good....

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