Mister Sub

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543 E Main St

Chillicothe, OH 45601

+1 (740) 774-7827

http://www.mistersub.net

Located in the charming town of Chillicothe, OH, Mister Sub is a beloved sandwich shop known for its mouthwatering creations and friendly atmosphere. As soon as you step inside, the aroma of freshly baked bread and sizzling meats will greet you, setting the stage for a delightful dining experience.

Whether you're craving a classic turkey and avocado sandwich or feeling adventurous enough to try their signature loaded Italian sub, Mister Sub offers a diverse menu to satisfy all taste buds. The cozy ambiance and quick service make it a perfect spot for a quick lunch break or a casual dinner with friends. Next time you're in Chillicothe, be sure to stop by Mister Sub for a delicious sandwich experience you won't soon forget.

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Reviews

4.545 reviews

Logan

5/29/2025

Home town restaurant at its finest. This place has been around since I was a kid and never disappoints. They have cold and hot subs so for those of you that are one sided your good lol.

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Myles K.

11/10/2023

Just stopped on our way through town at this spot. Thought it was more of a sub/deli sandwich spot but seemed like a pizza place that does subs, which wasn't a bad thing. You order at the...

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Justin C.

12/29/2024

Good food good service good time nice atmosphere clean bathrooms big parking mountain dew products

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Stephanie S.

6/23/2023

We were curious what was on the menu but couldn't find one online so we stopped by and took these photos to save others from the same problem. As soon as I opened the door I was surrounded by...

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Mike T.

12/4/2023

If you're looking for a non-chain sub-shop, this is your pick. Other reviews can regale you with their selections, but for me, it's the meatball sub, which reminds me of the grinders I've gotten...

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"Family owned & SO GOOD. If you don't want something on a sandwich just ask! I saw a weird guy who did a review leave a bad one because he CHOSE not to omit certain condiments lol. But he literally..."