Peter Bream Jr., MD, FSIR

Linh Ngo, FNP is a dedicated healthcare provider affiliated with UNC Health Care in Chapel Hill, NC. Specializing in Neurology, Linh offers expert care and support to patients in need. With a background in medicine and a focus on neurological disorders, Linh Ngo, FNP is committed to delivering high-quality healthcare services to the Chapel Hill community. Generated from their website's infomation

My current research emphasizes mechanisms by which resident bacterial subsets stimulate protective vs inflammatory mucosal immune responses. I use established and novel gnotobiotic murine models to identify protective vs aggressive resident bacterial subsets and to determine their mechanisms of action. We explore functional consequences of microbial communities in selectively colonized gnotobiotic mice and following fecal transplants using murine or human donors. Major initiatives explore therapeutic potential of existing and novel bacterial consortia in preclinical models, including humanized mice colonized by pooled IBD fecal transplants. The effect of diet on bacterial metabolic function/bacterial interaction are recent areas of interest. Parallel translational studies in IBD patients explore microbial biomarkers that identify risk of recurrence after Crohn’s disease surgery and onset of pouchitis after colectomy for ulcerative colitis. Mentoring and, career development are very meaningful activities for me. Fellowship training one-on-one in my laboratory and by directing a Basic Science T32 program and mentoring junior faculty are priorities.

Bradley V. Vaughn, MD is a renowned neurologist affiliated with UNC Health Care in Chapel Hill, NC. Specializing in neurology, Dr. Vaughn provides expert care and treatment for patients in the Chapel Hill area. Generated from their website's infomation