Panacea Coffee House Cafe & Roastery

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66 Commerce St
Waynesville, NC 28786

Panacea Coffeehouse Cafe & Roastery is a local coffeehouse and cafe located in downtown Waynesville, NC. They offer freshly roasted coffee, espresso drinks, and a variety of good eats, including sandwiches and salads.

With a focus on quality and taste, Panacea Coffeehouse Cafe & Roastery provides customers with a selection of whole beans sourced from Africa, Central America, South America, Asia, and the Pacific Islands. They also offer special roasts, decaf options, and a coffee club for those looking to have fresh roasted beans delivered to their homes monthly.

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4.5173 reviews
Photo of Rob M.
Rob M.
10/26/2025

Great coffee drinks, oat milk for vegan folks like us. Outdoor seating at creek is fantastic and cozy indoors. Super Service Love this place.

Photo of Catherine W.
Catherine W.
8/4/2025

Took our plant based family to lunch, we had salads and hummus, very delicious. The bagels are great too!

Photo of Tejaswini L.
Tejaswini L.
10/25/2024

We stopped here on the way and this definitely became the highlight of the day. Loved the vibe here... We were here on a weekday afternoon and it was so heartwarming to see groups of lovely women...

Photo of Elizabeth E.
Elizabeth E.
4/6/2025

We got the tres leche and it was so delicious. The shop has ample indoor and outdoor seating on a creek. Located in historic Frog Level this coffee shop is an absolute gem.

Photo of James S.
James S.
6/25/2025

I stopped in while passing through town and ate an early lunch and grabbed coffee. The local lox (trout) was good but they were out of bagels so we subbed for toast. There's black coffee ordered...

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United StatesNorth CarolinaWaynesvillePanacea Coffee House Cafe & Roastery

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