Choice Hotels

Newly remodeled! Welcome to the Holiday Inn Express in Greenville, NC! We invite you to experience a memorable stay with first-class amenities at one of the finest hotels in the area. Located in the heart of the Medical District, we are conveniently adjacent to ECU Medical Center, The Leo Jenkins Cancer Center, East Carolina Heart Institute, Brody School of Medicine, East Carolina Dental School, and other medical facilities. Our prime location places you just miles from East Carolina University, Dowdy Ficklen Stadium, Clark LeClair Stadium, Minges Coliseum, and Elm Street Park, making it easy to enjoy the best of Greenville. We’re also minutes away from major businesses like Thermo-Fisher Scientific, Catalent, Hyster-Yale, Grady-White Boats, Attindas, and Pitt Community College. Unlike other hotels in Greenville, we offer an array of complimentary amenities designed to enhance your stay. Enjoy our hot breakfast buffet, high-speed internet access, and meeting room space. Our Business Center and IHG Rewards Club points make conducting business effortless. Additionally, we are just 3 miles from Pitt Greenville Airport (PGV) and offer free airport shuttle service for your convenience. You’ll love our attention to detail as you "Stay Smart" at the Holiday Inn Express in Greenville, NC. We’re here to ensure that your stay is comfortable, productive, and enjoyable.