Toth Lab
Toth Lab, located in New York, NY, focuses on understanding the impact of environmental challenges on human health, particularly how factors like chronic stress, drug use, and adverse maternal environments contribute to common diseases. Through the use of mouse models, the lab aims to develop a theoretical framework that explains the mechanisms of environmentally induced epigenetic adaptation and its potential maladaptive consequences.
The research conducted at Toth Lab delves into the complexities of phenotypic adaptation that does not involve changes in DNA sequence, highlighting the significance of epigenetic factors in health outcomes. By investigating the long-term effects of these adaptations, the lab seeks to uncover the trade-offs that may lead to behavioral abnormalities and metabolic diseases.
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