Cook Microbiology Lab

The Cook Microbiology Lab, located in Vestal, NY, conducts vital research on Gram-positive bacteria, specifically Streptococcus pyogenes and Streptococcus agalactiae, which can lead to invasive infections as well as asymptomatic colonization in hosts. The lab's primary focus is to uncover the mechanisms behind the colonization of these bacteria on mucosal surfaces, examining the host signals that influence bacterial behavior and the resulting transcriptional changes.

Additionally, the Cook lab investigates the role of normal microbiota in the colonization and infection processes of GAS and GBS. To achieve their research goals, they utilize a variety of systems, including cell culture and mouse models, combined with molecular and -omics approaches to explore the interactions between host factors and bacterial colonizers.

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