Anca Askanase, MD

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161 Fort Washington Ave
New York, NY 10032
Dr. Anca Dinu Askanase recently joined the CUMC Rheumatology faculty where she is the founder and clinical director of Columbia's new Lupus Center and the Director of Rheumatology Clinical Trials. Dr. Askanase is an internationally renowned clinician, diagnostician and researcher with more than 15 years specializing in complex Systemic Lupus Erythematosus (SLE). Dr. Askanase trained as a rheumatologist at New York University where she remained for more than 15 years on faculty, directing clinical trials, training fellows and residents, and treating challenging cases of SLE at NYU's prestigious Hospitals. Dr. Askanase's academic career has focused primarily on the care of patients with SLE and other autoimmune diseases.In order to provide better care for patients suffering from these devastating diseases, she embarked on a journey of research and discovery, with the goal of understanding disease outcomes from both the patients' and physicians' perspective while helping to redefine 21st century therapeutic options. It is Dr. Askanase's hope that by helping to establish widely accepted parameters for quantifying the impact of the disease and the response to medications, all doctors will have effective benchmarks and therapeutic options to better treat patients with SLE's often confounding symptoms. In addition to numerous publications and benchmark clinical trials, Dr. Askanase is a member of the two major international consortia aimed at providing the collaboration between lupus doctors needing to improve outcomes and therapies in Lupus: the SLICC (SLE international Collaborating Clinics) and the LNTN (Lupus Nephritis Trial Network).Dr. Askanase believes that excellent care often involves bringing novel therapies to her patients with Lupus and other autoimmune diseases; thus, she has been involved in every major SLE clinical drug trial and multiple NIH and industry sponsored clinical trials. One of her most rewarding experiences was her involvement as the Site Principal Investigator in the registrational study that led to the FDA approval of Belimumab, the first new Lupus drug in over 50 years. Dr. Askanase also designed and executed the only study looking at a rational approach (based on pharmacogenetics and metabolite measurement) to use Azathioprine in the treatment of Lupus. She is currently evaluating the use of ACTH as a steroid alternative in lupus nephritis. Dr. Askanase is also a proud Columbia Alumnus and still lives in Morningside Heights with her husband and two children.
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Martin B. Leon, MD, is a distinguished medical professional with a significant presence in the field of interventional cardiovascular medicine. Currently, he holds the position of Professor of Medicine at Columbia University Irving Medical Center, and previously served as the Director of the Columbia Interventional Cardiovascular Care until July 2023. Presently, he fulfills the role of Chief Innovation Officer and the Director of the Cardiovascular Data Science Center for the Division of Cardiology. Dr. Leon actively practices as an interventional cardiologist at NewYork-Presbyterian Hospital in New York City. Furthermore, he is recognized as the Founder and Chairman Emeritus of the Cardiovascular Research Foundation.Throughout his career, Dr. Leon has played a pivotal role in shaping the field of interventional cardiovascular medicine through his involvement in over 50 clinical trials. Some notable studies include STRESS, STARS, Gamma-one, SIRIUS, ENDEAVOR, and the recent PARTNER trial, which focuses on evaluating the efficacy of transcatheter valve therapy for individuals with aortic stenosis. With an impressive portfolio of contributions, Dr. Leon has co-authored over 1550 publications and has performed more than 10,000 interventional procedures. His visionary leadership and innovative mindset have solidified his standing as a thought-leader in the expanding sub-specialty of interventional cardiovascular device and drug therapies.Dr. Leon is the esteemed Director and Founder of Transcatheter Cardiovascular Therapeutics (TCT), the preeminent global conference dedicated to interventional cardiovascular medicine. Recently celebrating its 35th anniversary, TCT continues to be at the forefront of advancing knowledge in this field. Additionally, he has directed or co-directed over 100 international educational programs focused on interventional cardiology. Dr. Leon's significant contributions to the medical community have been recognized with 10 international career achievement awards, and he has been awarded an honorary degree from the University of Athens.In his earlier roles, Dr. Leon served as the Director of Cardiovascular Research and Education at the Lenox Hill Heart and Vascular Institute in New York. Prior to that, he held the position of Director of Clinical Research at the Washington Cardiology Center, based at the Washington Hospital Center, and served as a Clinical Professor of Medicine at Georgetown University Medical Center in Washington, DC. Early in his career, he played instrumental roles as a Clinical Associate, Senior Investigator, and Director of the Catheterization Laboratories in the Cardiology Branch of the National Heart, Lung and Blood Institute at the National Institutes of Health in Bethesda, MD. He was also involved in founding the Washington Cardiology Center and the Cardiology Research Foundation in Washington, DC.Dr. Leon completed his Cardiology fellowship at Yale-New Haven Hospital, following his medical education at the Yale School of Medicine. He further pursued his internship and residency in internal medicine at the Yale-New Haven Hospital.
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