Chrai Associates Inc

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Enterin, Inc is a pioneering pharmaceutical company based in Philadelphia, PA, with a groundbreaking mission to develop a revolutionary drug that repairs the dysfunctional gut-brain axis in patients suffering from neurodegenerative diseases. Their lead molecule, ENT-01, has shown promising results in preclinical models of Parkinson's Disease by displacing -synuclein aggregates and restoring normal signaling between the gut and the brain. With recent success in meeting its primary endpoint in a Phase 2b study for Parkinson's Disease patients, Enterin's clinical data suggests that repairing the gut-brain axis can significantly enhance the quality of life for individuals affected by Parkinson's Disease and other neurodegenerative conditions, by addressing multiple non-motor symptoms. Driven by a vision of providing new hope against Parkinson's, autism, and other neurodegenerative diseases, Enterin is at the forefront of scientific research and development in this field.Generated from the website

Carisma Therapeutics Inc. is a Philadelphia-based biotech company that is revolutionizing cancer treatment through the development of CAR-Macrophages, a groundbreaking approach to immunotherapy. By engineering monocytes and macrophages to attack tumors, Carisma's innovative cellular therapies have the potential to deliver long-term anti-tumor immunity and significantly improve patient outcomes. With a focus on leveraging advances in macrophage biology, chimeric antigen receptor engineering, and adoptive cellular therapy, Carisma's unique therapeutic approach engages both the innate and adaptive immune systems to launch a multi-pronged attack on tumors. By addressing key challenges faced by current cell therapies, such as tumor infiltration, immunosuppressive tumor microenvironments, and antigen heterogeneity, Carisma is at the forefront of developing life-changing treatments for patients with cancer and other serious disorders.Generated from the website