Holiday Inn Express & Suites Cape Girardeau I-55 by IHG

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3253 William St
Cape Girardeau, MO 63703
Check-in: 3 PM, Check-out: 11 AM
Welcome to Our Cape Girardeau Hotel. Just off I- 55 at exit 96, the Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers hotel guests 102 spacious, contemporary suites. Vacation and business guests alike choose these accommodations for a comfortable and convenient stay. Our Cape Girardeau, Missouri hotel is just minutes from Southeast Missouri State University, where guests are encouraged to cheer on the Redhawks in football and basketball. We're also only 10 miles from Trail of Tears State Park, so families can enjoy picnics, hiking, biking and fishing. Be sure to stop by our Old Downtown area where you will not only enjoy a variety of shops and restaurants, but you can enjoy the great view of the Mississippi River. Business travelers appreciate our Cape Girardeau, Missouri hotel's convenient location close to St. Francis Hospital, Southeast Missouri Hospital, Doctors Park, the Show Me Center, Procter & Gamble, Mondi, Shawnee Park and Biokyowa. We provide two spacious meeting rooms, as well, which feature A/V equipment ideal for business functions or special events. With the help of our professional staff, your event can be a success. At our Girardeau hotel, we know it's the extra perks that make your stay unforgettable. We provide an indoor pool and well-equipped fitness center to help you relax and unwind. Be sure to stop by our breakfast bar each morning, too, for biscuits, eggs, fruit and our signature cinnamon rolls. We look forward to your next visit!
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Reviews

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4.534 reviews
Photo of Philip L.
Philip L.
8/22/2024

Stayed here twice this year and had a great experience both times. The hotel is very clean and has a spacious lounge and dining area. The staff are also super friendly, professional, and...

Christina S.
10/22/2025

Beautiful lobby and clean rooms. Great breakfast and cookies and milk served in the evening by a lovely lady. What a treat!

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Karrah T.
3/17/2025

This is a must stop! I have stayed here twice now and each time has been awesome. The beds are so comfortable and the pillows are top notch I usually bring my own and I have used the hotels over...

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Macie R.
8/28/2022

Made a stop here as half way point to my Memphis trip!! Let me start by mentioning that front desk was PERFECTION !!! They quickly and easily got us to our room , I was wowed upon opening my door...

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Ron P.
6/19/2023

The place is very clean and the staff is very friendly and working hard, the complementary food was amazing the mash potatoes are the best along with the meat balls in gravy, very well kept and...

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United StatesMissouriCape GirardeauHoliday Inn Express & Suites Cape Girardeau I-55 by IHG

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