Drury Inn & Suites Sikeston

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2608 E Malone Ave
Sikeston, MO 63801
Travel Happy® with free hot breakfast, 5:30 Kickback® with dinnertime snacks and cold drinks, Wi-Fi, popcorn and soda, a business center, a workout facility, and more. A microwave and refrigerator can be found in all rooms. Drury Hotels is 100% family-owned and operated. At every one of our 150+ locations in 26 states, you'll consistently experience rooms with crisp sheets, fine linens, and cozy surroundings to ensure a good night's sleep.

Reviews

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4.038 reviews
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Adrienne J.
9/3/2025

Last minute reservation as we traveled home from florida. Beautiful room, comfortable beds and clean. Morning reservation/front desk crew Amazing! Our new go-to hotel

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Nichole M.
1/2/2025

I enjoy staying at the Drury INN when I travel. They have excellent customer service (by Laurie), the establishment is well decorated, there is plenty of parking, they have a bottle refill...

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Richard B.
4/11/2024

Having lived in Europe for the past 30+ years, I had not heard of Drury Hotels. I booked a room for two nights in Sikeston, Missouri. My goodness was I in for surprise. The Drury inn and suites...

Sherry A.
9/6/2025

July 2025 Drury Inn & Suites Sikeston Sikeston (((Heartless, cruel manager came to room w cop while I was in bed having autoimmune disease episode w papers of diagnosis in my hand to throw me in...

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Vickey H.
5/13/2025

We absolutely loved our stay at Drury Inn & Suites. So clean and at a very reasonable price! We will book with Drury Inn whenever possible.

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