The Pellman Laboratory

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450 Brookline Ave Ste 663
Boston, MA 02215
+1 (617) 582-4300
https://pellmanlab.dana-farber.org

The Pellman Laboratory, located in Boston, MA, focuses on the study of cell division and chromosome segregation errors in cancer, exploring how these errors impact cancer genome structure. Utilizing genetics, biochemistry, and live cell imaging, the lab has developed innovative methods to link morphological phenotypes directly to a cell's genotype.

By employing techniques such as long-term live cell imaging combined with single-cell isolation and genomics, the Pellman Laboratory investigates catastrophic mutational processes that contribute to rapid genome evolution in cancer. Their research aims to dissect the mechanisms behind chromothripsis and other genomic instabilities, advancing the understanding of cancer biology.

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