Smith & Nephew

NxStage Medical is a medical device company that develops, manufactures and markets systems for the treatment of end-stage renal disease and acute kidney failure. The company s product for chronic renal care is the NxStage System One, which is one of the first truly portable hemodialysis systems cleared for home use. The system offers patients the chance to enjoy the health benefits of daily hemodialysis, either at home or on the road. Its products for acute renal care include an NxStage System One version, which was designed to simplify the delivery of renal care in acute settings. It gives clinicians the flexibility to deliver the more intensive renal therapies they believe will help their patients, while reducing the strain on overburdened critical care staff and resources. NxStage Medical is located in Lawrence, Mass.

Fresenius Medical Care North America is part of Fresenius Medical Care, one of the world's largest, integrated providers of products and services for individuals with chronic kidney failure, a condition that affects more than 1.5 million individuals worldwide. Through its network of over 2,220 dialysis clinics in North America, Europe, Latin America and Asia-Pacific, Fresenius Medical Care provides dialysis treatment to 172,227 patients around the globe. Fresenius Medical Care is also the world's largest provider of dialysis products, such as hemodialysis machines, dialyzers and related disposable products. Fresenius Medical Care can trace its roots back to 1462, when The Fresenius family assumed ownership of Hirsch Pharmacy in Frankfurt, Germany. Approximately two-thirds of the company's research and development activities are based in Germany and one-third in North America. The company holds rights to more than 1,100 patents and patent applications relating to dialysis technology in major markets and own trademarks throughout the world.

Founded in 1983 and headquartered in Burlington, Mass., LeMaitre Vascular specializes in the manufacturing and distribution of devices for the treatment of peripheral vascular diseases. It serves various health care organizations and vascular surgeons and interventionalists. The company provides a wide range of products, such as the AnastoClip vessel closure systems used in vascular anastomosis. LeMaitre Vascular additionally provides other devices used by vascular interventionalists in performing a variety of angiographic procedures including venous and arterial vascular studies. It also offers EndoFit thoracic stent grafs for thoracic endovascular aortic repair procedures. LeMaitre Vascular additionally offers InvisiGrip vein strippers and valvulotome and Pruitt-Inahara carotid shunts used in bypass surgeries.