Hla Laboratory at Boston Children's Hospital

Boston Children's in Boston, MA has always embodied a culture of innovation and scientific discovery, with the goal of improving the lives of children and families. This legacy continues today as we lead the world in pediatric research, empowering our clinicians and scientists to challenge the status quo and seek better answers for children everywhere.

Led by Caterina Stamoulis, PhD, our laboratory is involved in a wide range of studies in Computational Neuroscience. We develop novel signal processing, mathematical and statistical methods and models with the goal to characterize brain dynamics and networks from high-dimensional brain data. Research in the laboratory lies at the intersection of Neuroscience and Data Science and aims to address fundamental questions in Cognitive and Systems Neuroscience using Big Data.

The broad interest of the Kim Lab is to characterize the biology of stem cells in normal lung and lung cancer. Numerous lung diseases such as cystic fibrosis or chronic obstructive pulmonary disease involve injured or depleted bronchiolar or alveolar epithelium. Bronchiolar and alveolar cells are also affected in adenocarcinoma, the most common form of lung cancer. It is likely that lung stem cells are critically affected in patients with these devastating diseases. Our long-term goal is to elucidate the role of stem cells in lung homeostasis as a prerequisite to the development of therapeutic strategies that can be used to prevent or attenuate lung disease.