Chartoff Lab

Website
115 Mill St
Belmont, MA 02478
https://www.chartofflab.com

Chartoff Lab, part of the Basic Neuroscience Division at McLean Hospital and affiliated with Harvard Medical School, focuses on understanding the molecular, cellular, and circuit-based mechanisms behind drug dependence and withdrawal. The laboratory employs animal behavioral models to explore how chronic drug exposure alters the brain, resulting in negative affective signs that enhance relapse risk in the context of substance use disorders.

The research team investigates sex differences in addiction behaviors, recognizing significant disparities in the addiction cycle between males and females. By mapping neural circuits and studying the effects of biological sex on addictive behavior, Chartoff Lab aims to contribute valuable insights to the field of neurobiology and motivated behavior.

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