Channing Laboratory

The overall goal of the Sampson Lab is to help improve the health of children with nephrotic syndrome through applied genomics, with a focus on samples and data collected from patients with this condition. We use computational genomics and bioinformatics to discover new, and map known, nephrotic syndrome-associated variants. We use systems genomics to integrate this genetic data with other genome-scale molecular datasets to try to understand the mechanisms linking these genetic changes with disease. And we use epidemiology to discover the clinical consequences for patients carrying disease-associated genetic variants.

Berde Laboratory, located in Boston, MA, is a renowned research group within the Department of Anesthesiology, Critical Care, and Pain Medicine. Led by Professor Charles Berde, MD, PhD, the lab focuses on pediatric anesthesiology and the management of acute and chronic pain in children. Their clinical research areas include the pharmacology of analgesics and local anesthetics, neurophysiology of general anesthesia in children, clinical outcomes of neuropathic and cancer pain treatment, and functional brain imaging of children with neuropathic pain. Their translational research has successfully progressed from the laboratory to clinical trials, particularly in the development of novel prolonged duration local anesthetics. With a commitment to advancing knowledge and improving patient care, Berde Laboratory is at the forefront of pediatric pain management research.Generated from the website