Boston Clinical Laboratories

Boston Children's in Boston, MA has always embodied a culture of innovation and scientific discovery, with the goal of improving the lives of children and families. This legacy continues today as we lead the world in pediatric research, empowering our clinicians and scientists to challenge the status quo and seek better answers for children everywhere.

The Snapper Laboratory is located in the division of GI/Nutrition in the Enders Research Building at Boston Children

The overall goal of the Sampson Lab is to help improve the health of children with nephrotic syndrome through applied genomics, with a focus on samples and data collected from patients with this condition. We use computational genomics and bioinformatics to discover new, and map known, nephrotic syndrome-associated variants. We use systems genomics to integrate this genetic data with other genome-scale molecular datasets to try to understand the mechanisms linking these genetic changes with disease. And we use epidemiology to discover the clinical consequences for patients carrying disease-associated genetic variants.