Ruth A. Karron, MD

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1800 Orleans St
Baltimore, MD 21287
Gastroenterologist Mouen Khashab specializes in therapeutic endoscopy, and he oversees this group of practitioners across the Johns Hopkins enterprise. Nationally and internationally known in the field of interventional endoscopy, Dr. Khashab has contributed immensely to the field’s advancement as a minimally invasive means to treat gastrointestinal and pancreaticobiliary disorders. Dr. Khashab earned his medical degree from the American University of Beirut Faculty of Medicine, and subsequently completed a residency in internal medicine and a fellowship in gastroenterology at Indiana University. He then completed a two-year fellowship at The Johns Hopkins Hospital before joining the faculty in 2011. A busy researcher, Dr. Khashab has published more than 600 papers in peer-reviewed journals. In 2013, he described the procedure called gastric peroral endoscopic myotomy (known as G-POEM) and was able to disseminate and teach it all over the world. Other procedures that he expanded include peroral endoscopic myotomy (POEM), peroral endoscopic myotomy with fundoplication (POEM-F), Zenker’s peroral endoscopic myotomy (Z-POEM) and full thickness resection. In 2022, he received the Master Endoscopist Award from the American Society for Gastrointestinal Endoscopy (ASGE) for his numerous contributions to the field. His procedural expertise includes endoscopic retrograde cholangiopancreatography (ERCP), endoscopic ultrasound (EUS), interventional EUS, submucosal endoscopy, POEM/achalasia, endoscopic mucosal resection, endoscopic submucosal dissection, luminal stenting, large polyp resection and Barrett’s therapy, among others. Dr. Khashab is involved with multiple gastrointestinal societies and has served on many committees, including the ASGE Standards of Practice Committee, which is in charge of formulating guidelines for the practice of endoscopy. He has also served as an associate editor for the journal Endoscopy, a premier journal in the field. Khashab is a highly sought-after speaker at national and international conferences, and he has participated in multiple live endoscopy conferences. Outside of academic medicine, Dr. Khashab is an entrepreneur. His major interest is in new technology and medical devices, and his goal is to disrupt the field by introducing technology that makes endoscopic procedures safer, easier, efficient and more scalable.
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Dr. Ie-Ming Shih is the Richard TeLinde Distinguished Professor in the Department of Gynecology and Obstetrics at the Johns Hopkins University School of Medicine. Dr. Shih directs the inter-departmental TeLinde Gynecologic Disease Program and co-directs the Women‘s Malignancy Program at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Medical Institutions. He is the Principal Investigator of the NIH Specialized Program of Research Excellence (SPORE) of Ovarian Cancer focusing on concept-driven clinical trials and early detection of the disease. Dr. Shih's research has been continuously supported by National Institute of Health.Dr. Shih received his M.D. from Taipei Medical University and earned his Ph.D. from the University of Pennsylvania. Dr. Shih went on completing a clinical fellowship in gynecologic pathology and a research fellowship in cancer genetics at Johns Hopkins before joining the faculty in 2001.The scientific contributions from his team include 1) molecular characterization of different types of ovarian cancer, 2) elucidation of the origin and evolution trajectory of ovarian precancerous lesions, 3) the discovery of cancer- promoting genes that are amenable for targeting, 4) the etiology of endometriosis and 5) the pathogenesis of gestational trophoblastic neoplasm. Dr. Shih has published more than 360 original publications and book chapters related to basic and translational cancer research, especially in the study of gynecological malignancies. He has received the 2017 Most Influential Research Paper Award in gynecologic diseases by the Columbia Hospital Foundation, and several research awards from the Tina’s Wish Bozeman Foundation, Gray Foundation, and the Endometriosis Foundation of America to support and recognize his research works.He sits in several advisory/editorial boards such as the World Health Organization (WHO) Nomenclature Committee for Gynecologic Neoplasms and the NCI Ovarian Task Force of Gynecologic Cancer Steering Committee. Besides his clinical, research and teaching obligations, Dr. Shih is a passionate photographer.
Jim C. Fackler, MD
Internal medicine practitioners

Jim C. Fackler, MD

Dr. James Fackler is a professor of anesthesiology and critical care medicine at the Johns Hopkins University School of Medicine. His areas of clinical expertise include acute respiratory distress syndrome, novel respiratory therapies, and critical care informatics.Dr. Fackler received his undergraduate degree in biology from the University of Illinois and earned his M.D. from Rush Medical College in Chicago. He completed his residencies in pediatrics and anesthesiology and then fellowships in pediatric intensive care and pediatric anesthesia at the Johns Hopkins University School of Medicine. His first faculty position was at the Children's Hospital in Boston where he was an early leader in use of the internet for health data exchange and critical care monitoring.Dr. Fackler returned to the Johns Hopkins faculty in 1996 to run the Extracorporeal Membrane Oxygenation program and Respiratory Therapy.He took a "sabbatical" from 2002 to 2006 and worked for the Cerner Corporation developing their critical care and device integration solutions. He has founded three health care informatics-based startups and consults for other device and information integration companies.Dr. Fackler's research interests include optimizing team performance in pediatric critical care. He has mentored pediatric residents, critical care fellows, and biomedical engineering undergrads, Masters and PhD students. His current major focus is on sepsis.He serves as an associate editor for Pediatric Critical Care Medicine and as an ad hoc journal reviewer for many notable publications including New England Journal of Medicine and Critical Care Medicine. He is a member of American Association of Artificial Intelligence, American Medical Informatics Association and the Society for Critical Care Medicine. He helped found, and is on the Board of the non-profit, Machine Learning for Healthcare.Dr. Fackler is a frequent lecturer and panelist on the subject of critical care informatics. He is an expert in data integration and its use.
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