Jean Kim, MD

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4940 Eastern Ave Ofc
Baltimore, MD 21224
Jean Kim is a surgeon-scientist whose clinical and translational research area of interest is in the pathogenesis of chronic rhinosinusitis with nasal polyposis. She cares for patients with the most severe forms of chronic rhinosinusitis, including patients with sinus disease, nasal polyposis and severe asthma. She also has expertise in the management and study of patients with autoimmune disease and complex sinus disease. Dr. Kim is co-director of the Jerome L. Greene Sjögren’s Disease Center, and is lead consultant for the Johns Hopkins Vasculitis Center and the Primary Ciliary Dyskinesia Foundation Clinical and Research Center at Johns Hopkins. She has considerable experience in conducting clinical trials in sinus and autoimmune diseases. With an active basic and translational research laboratory that studies the underlying mechanisms of airway epithelial dysfunction in sinus disease, Dr. Kim’s work is nationally and internationally recognized in the field of epithelial cell biology and allergic immune responses. She has held sponsored grants from the National Institutes of Health, various foundations and pharmaceutical companies to conduct her clinical, basic and translational research. Additionally, Dr Kim is interested in researching the pathogenesis of climate factors contributing to nonallergic rhinitis. Dr. Kim earned her medical and doctoral degrees from the University of Pittsburgh, and she completed her residency and fellowship training at the Johns Hopkins University School of Medicine. She is a member of the editorial board of the International Forum of Allergy and Rhinology, the nationally #1 ranked rhinology journal. Dr. Kim has served as a study section reviewer for the Medical Research Council of the United Kingdom, the Flight Attendant Medical Research Institute foundation and the Johns Hopkins Institute for Clinical and Translational Research, and she has received Johns Hopkins University School of Medicine Clinician Scientist Career Development Awards.
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Simon R. Best, MD
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Simon R. Best, MD

Laryngologist Simon Best specializes in voice and airway disorders, including the comprehensive care of professional voice-users and performers. He treats patients diagnosed with recurrent respiratory papillomatosis (RRP), vocal cord paralysis, laryngeal cancer, precancerous vocal cord dysplasia, benign laryngeal lesions (polyps, cysts, nodules), and laryngeal and tracheal stenosis. He has expertise in the operative management of vocal cord disorders, including Blue Light laser surgery and office-based management of vocal cord papilloma, dysplasia and vocal cord paralysis. Dr. Best earned a medical degree from the Yale School of Medicine and completed residency training in Otolaryngology–Head and Neck Surgery at the Johns Hopkins University School of Medicine. He undertook fellowship training in laryngology at Massachusetts General Hospital. Dr. Best has a particular clinical and research interest in recurrent respiratory papillomatosis and sees patients from across the country for specialized care for this disorder. He offers operative and office-based laser for papilloma, utilizing the Blue Light laser, which allows for precise excision of papilloma while preserving underlying vocal function. Dr. Best is also a pioneer in the adjuvant use of bevacizumab for RRP, helping many patients break the cycle of repeated surgeries. The Best Laboratory studies RRP and the development of novel immunotherapies to target the underlying viral infection. This research is conducted in collaboration with the head and neck cancer and cervical cancer research groups at Johns Hopkins, which also study human papillomavirus-related diseases. In addition, Johns Hopkins is a site for ongoing clinical trials in DNA immunotherapy, the goal of which is to eliminate the causative viral infection that leads to RRP.
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