James Eshleman Jr., MD

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1800 Orleans St
Baltimore, MD 21287
Dr. James Eshleman is a professor of pathology and oncology at the Johns Hopkins University School of Medicine and a member of its Kimmel Cancer Center. His areas of clinical expertise includes molecular diagnosis. Dr. Eshleman serves as the associate director of the Molecular Diagnostics Laboratory at the Johns Hopkins School of Medicine. Dr. Eshleman earned his M.D. and Ph.D. from the University of Pennsylvania School of Medicine. He completed a residency in clinical pathology and a fellowship in blood banking and transfusion medicine at the Hospital of the University of Pennsylvania. His research interest is genetically killing pancreatic cancer using CRISPR-Cas9 by targeting somatic mutations, and developing new molecular pathology tools.
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Dr. Angelo De Marzo is a professor of pathology, oncology and urology at the Johns Hopkins University School of Medicine. His areas of clinical expertise include pathology and prostate cancer. Dr. De Marzo serves as the Deputy Director for Anatomic Pathology in the Department of Pathology, and Co-Director of the Immunohistochemistry Clinical Lab in Johns Hopkins Hospital. He also serves as the Associate Director of Cancer Research Pathology at the Sidney Kimmel Comprehensive Cancer Center. Dr. De Marzo founded the Tissue Microarray Core at Johns Hopkins, now known as the Oncology Tissue Services. He led it for a decade and now serves as an advisor to the core. Dr. De Marzo's research interests include the molecular pathobiology of prostate cancer, biospecimen banking, and biomarker development, especially using immunohistochemistry, in situ hybridization and multiplex IHC and image analysis. Dr. De Marzo received his B.A. in molecular, cellular and developmental biology and psychology from the University of Colorado at Boulder. He earned his M.D. and Ph.D. in experimental pathology from University of Colorado Health Sciences Center. He completed his residency in pathology at the Johns Hopkins School of Medicine and performed a fellowship at the Brady Urological Institute at Johns Hopkins. Dr. De Marzo joined the Johns Hopkins faculty in 1998. Dr. De Marzo served as Chief Medical Officer at Predictive Biosciences Inc. from 2011-2013. He served as an Associate Editor for the Journal of Clinical Investigation from 2017-2022. He currently serves on the editorial boards of the journals, The Prostate and Cancer Prevention Research. He is the recipient of the 2004 Donald S. Coffey Prostate Cancer Foundation Physician/Scientist Award and The Professors Award for Teaching Excellence at The Johns Hopkins University School of Medicine (2022). He is an elected member of the Association of American Physicians (2018) and is a member of various professional organizations, including the American Urological Association and the American Association for Cancer Research.
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