Cj S.
9/30/2025
Love the shrimp poor boys and a cold beer. Great location right next to Canal street.
Mike Serio's Po-boys
$$
Open
(208)
Photos
133 Saint Charles Ave
New Orleans, LA 70130
Mike Serio's Po-boys is a casual dining establishment in the heart of New Orleans, Louisiana, known for its traditional po-boy sandwiches.
With a focus on quality ingredients and authentic flavors, the restaurant offers a variety of classic and specialty po-boy options to satisfy any craving.
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Reviews
3.5208 reviews
De A.
10/15/2025
Friendly greeting by the fry cook. We stopped in to try a Po-boy and a Muffaletta (sp?). My partner said her muffaletta was perfect. My fried catfish po-boy was okay. Razor thin tomato slice and...
Craig F.
9/27/2025
Close to hotels so an appealing stop for lunch. It's a LSU shrine so great if you're a fan. Sandwich was a disappointment. Hot roast beef was more than 50% gravy, little meat, very soggy. Chips...
Don P.
9/24/2025
Service was good, food was absolutely disappointing and a complete rip off. Do yourself a favor don't go spend your time and money elsewhere.
Michelle K.
5/29/2022
TLDR: Definitely get the roast beef & check in on yelp for a free drink! Roast beef: I was expecting roast beef slices but it was like a stewed beef in shreds with lots of juice (like au jus)....
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