Ted R.
6/15/2025
Large shrimp po' boy dressed was huge and one of the best I've had. Worth $16. Delicious fries too. They serve Abita Turbo Dog, which goes well with the eats! Merch and memorabilia celebrating...
Domilise's Po-Boys
$
Open
(743)
Photos
5240 Annunciation St
New Orleans, LA 70115
Domilise's Po-Boys and Bar, established in 1918, is a cherished fixture in the Uptown neighborhood of New Orleans. The family-owned establishment is renowned for its delectable po-boys, serving the community with a dedication to tradition and exceptional hospitality spanning generations.
The legacy began with Peter and Sophie Domilise, later nurtured by Dorothy "Miss Dot" Domilise and her family, who continue to welcome both locals and tourists alike as part of their family. Through the highs and lows of New Orleans history, Domilise's has remained a beloved haven where memorable meals and enduring kinship thrive.
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Reviews
4.0743 reviews
Stephen L.
10/7/2025
(10/07/2025) No frills Po' boy shop. I got the half and half seafood sandwich (half shrimp and half oyster). The oysters were fine, but not particularly flavorful; the shrimp were crispy on the...
Shelly R.
7/14/2025
I'm always on the search for the best poboy when I'm in New Orleans. I saw a clip or program short about Domilise. I had to get there. I didn't have a rental car this trip so I used public...
Haeun J.
10/11/2025
Super underwhelming poboy especially after a 1.5 hour wait. If they were any faster, this might be worth it but it's really not worth it by any means. No seating to wait outside or a clear system...
Tom B.
2/17/2025
Heavens, what can be said about this place. It is an experience beyond all lunch places imaginable It was so packed and chaotic that one could hardly move. Everyone kept an even cheerful tone,...
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