Lesley P.
9/23/2025
Very pretty brewery! Great choice of beer and nice bartender, she was great. Currently it is a challenge to get there because of road construction, but we made it anyway!
Twisted Vine Brewery
$
Closed
(57)
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112 SE 4th St
Des Moines, IA 50309
Twisted Vine Brewery in Des Moines, IA welcomes guests with a penchant for exploration and a taste for distinctive craft beers. The brewery offers an inviting atmosphere where patrons can enjoy a variety of uniquely twisted brews crafted on-site. With a spacious tap room capable of accommodating up to 200 people, Twisted Vine is a versatile venue for private or semi-private events.
At Twisted Vine Brewery, the focus is on providing a memorable experience for visitors, whether they are seasoned beer enthusiasts or newcomers to the craft beer scene. The brewery's commitment to quality and creativity shines through in their innovative beer offerings and dedication to fostering a community of beer lovers in Des Moines. With a prime location in the heart of the city, Twisted Vine Brewery stands out as a must-visit destination for those seeking a fresh and flavorful beer experience.
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Reviews
4.557 reviews
Heidi H.
12/3/2024
I had never been to the Twisted Vine. I had been wanting to check this place out since they opened. I came down for a baby shower. It was a great space. The shower had the run of the place....
Tom B.
8/31/2025
Great dog friendly patio with nice view of the state capital building. Beer is tasty and plenty of available options (my vote is Bob's Ale). Plenty of available parking, but area is currently...
Matthew J.
8/9/2022
If you haven't been to Twisted Vine Brewing - you should check it out. Their new location in downtown Des Moines in East Village is killer. They have two bars on the inside, a large outside area...
Michael P.
9/16/2023
Stopped in today for a flight of craft brews. The building is absolutely beautiful. The bartender was attentive and even designed my flight of IPAs. If you find yourself in the area, check it...
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