Christine T.
8/16/2025
Be sure to go on the days they have cinnamon rolls....absolutely wonderful!! Also beware of over ordering. Everything is absolutely supersized. My husband and I could have easily shared one...
Sisters Mainstreet Cafe
$
Closed
(5)
Photos
312 Grand Ave
Spencer, IA 51301
Sisters Mainstreet Cafe is a cozy eatery located in Spencer, IA, offering a welcoming atmosphere for locals and visitors alike. With a focus on delicious comfort food and friendly service, this cafe is a popular spot for breakfast and lunch.
Guests can enjoy a variety of classic dishes at Sisters Mainstreet Cafe, all served in a charming setting that exudes small-town charm. Whether stopping by for a quick bite or a leisurely meal, patrons can expect a satisfying dining experience at this beloved cafe.
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Reviews
3.05 reviewsJamie H.
7/21/2022
Great mom and pop joint. It's a must if you in Spencer. Chicken fried steak and eggs , with home made bread. Happy as a pig mud!!
Jeff H.
2/18/2015
Was in town with my wife on business from California and we were looking for breakfast. There were only a few cafes listed on Yelp but we saw this place while driving through town and decided to...
Tarzan S.
9/2/2015
Reading the other review we were excited to try their breakfast. We were late and made it for lunch. Our mistake. Completely empty except for one other regular. The waitress was sloppy and a...
Jeon K.
9/24/2017
I won't go into detail but the old standard of a sixties lunch grill is still in operation here. I will say the location is a big plus as the shopping area is first rate.
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