Zimmer, Inc

Operational since 1988, Serim Research Corporation develops, manufactures, and markets test strips based on Serim's dry reagent technology. Located in Elkhart, Ind., it offers an array of products, including dialysis, diagnostics - PyloriTek, infection control - DISINTEK XL, food safety and sanitation - monitor strips. The company has created and developed technology, which includes colorimetric chemistries, reagent/membrane impregnation and test strip fabrication. Serim Research Corporation has a fully integrated Research & Development/Manufacturing Center and a new, state-of-the art, 32,630-square-foot, FDA-registered facility. It is ISO 9001:2000 and ISO 13485:2003 certified.

Biomet designs, manufactures and markets a range of medications for musculoskeletal-related complications. The company s product portfolio includes reconstructive products, including orthopedic joint replacement devices, dental reconstructive implants, and bone cements and accessories. It serves clients in more than 100 countries in Asia, Africa, North America, South America and Europe. Biomet also offers a selection of electrical bone growth stimulators and internal and external orthopedic fixation devices. The company provides fluid management products under the trade names of ArthroSorb, AquaLoc, Absorb-O-Mat and PowerPump. In addition, it offers pediatric femoral locking nails to address pediatric femur fractures in children. Biomet has annual sales of over $2 billion. The company s subsidiaries include Biomet 3i and Biomet Microfixation.

History of OrthoPediatricsThe concept for OrthoPediatrics originated in the mid 1980's by Nick Deeter as a business idea to provide better splinting and bracing for orthopedic problems in children. Because of the highly competitive nature and low margins, the business never materialized. During the period between the mid 1980's and the formalization of OrthoPediatrics, Mr. Deeter continuously monitored the pediatric orthopedic industry. He felt that because the trend for implantable devices in adults was becoming the norm, healthcare providers would eventually move toward some of the same philosophies in children.Beyond the trend to use implantable hardware rather than casting and bracing in children, the last decade has given way to regulatory reform enabling pediatric orthopedic products a high priority path through the FDA. The declaration of the Juvenile Arthritis as a National Healthcare Priority in a bill signed by President Clinton in October, 2000, the Medical Devices Technical Corrections Act of 2004, and the Pediatric Medical Device Safety and Improvement Act of 2007 have helped remove some of the barriers to increase the availability of devices for the treatment of conditions affecting children, thus allowing OrthoPediatrics the opportunity to effectively and exclusively focus on this small niche within the orthopedics industry.The current state of the pediatric orthopedic market is one of unmet needs and frustration among caregivers. Science suggests implantable devices are the best treatment for many conditions. However, regulatory agency barriers are just now reforming enough to allow reasonable economic entry for device manufacturers into the pediatric market. The pediatric market is much smaller than the $28 billion world-wide adult orthopedic market ; hence all the established orthopedic manufacturers are not interested in serving what was a $400 million US market in 2006.OrthoPediatrics was formally established in 2006 when Mr. Deeter formed a business team of orthopedic experts in engineering, marketing, regulatory, finance and manufacturing from Warsaw, Indiana, the "Orthopedic Capital of the World" and home to industry giants like Zimmer, Biomet and Johnson & Johnson's DePuy Orthopaedics. In order to ensure the clinical success of the devices, Mr. Deeter requested the help of many elite pediatric orthopedic surgeons from around the country. Together, the business team and surgeon experts are inventing and designing superior orthopedic implants for children.Mr. Deeter's extensive background in orthopedics and technology transfer, coupled with his company start-up skills and global surgeon contacts brings the OrthoPediatrics concept to life as "The Smallest Company in Orthopedics ".