Uno Pizzeria & Grill

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4740 E Southport Rd
Indianapolis, IN 46237
+1 (317) 791-8667
https://www.unos.com
Uno draws its identity and inspiration from the artisan heritage of the original Pizzeria Uno in Chicago, IL. Each restaurant still makes their Deep Dish Pizza dough fresh every morning. Our Chicago Thin Crust Pizzas are jam-packed with bold flavors. And our new Detroit Style Pizza, with its square shape, crunchy and crispy cheese-baked edge and light and airy crust, is a new favorite among our guests. We offer pizzas that are perfect for all meat-lovers, vegans, and gluten-free guests alike!Today, we are as passionate about craft beer as we are our pizza. We work with quality brewers to bring you a selection of some of the best national, regional and local craft beers. Nothing goes better together than pizza and beer!Our menu also features UNO favorites like the Shrimp & Crab Dip and Rattlesnake Pasta as well as a variety of other apps and pastas, salads, burgers and sandwiches, and entrees.

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3.5121 reviews
Photo of Doug H.
Doug H.
9/21/2025

Wow!!!! Just found another reason why I love UNO! It's always been one of my favorites on the southside. They offer a deal called TASTY TRIOS. It's offered all day everyday for only...

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Susan B.
7/2/2025

I've been to this Uno's location multiple times, and the servers are consistently fantastic -- friendly, attentive, and clearly care about their jobs. The food is solid, and the dining experience...

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Iva H.
9/21/2025

We decided to take advantage of the game day specials at Uno and got a great deal. They offer 3 different tasty trios every day and game day beer, wine, and cocktails. The tasty trio was Caesar...

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Sav M.
4/26/2025

The waiting time are awful. The food tasted amazing today but 15 minutes for a milkshake, the non-alcohol version a little bad! But the quality and taste was pretty great! Service was great as...

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John P.
9/16/2024

This is the first time I have been to this pizzeria Uno in a long time. Deep dish pizza is one of my favorites and the first deep dish I ever had was the pizzeria Uno in Chicago. This is the local...

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