Hashinolab

The Hashino-Nelson Lab at Indiana University focuses on the research and development of the neurosensory systems, particularly the inner ear, using human pluripotent stem cells in 3D culture. Their innovative use of organoids aims to replicate the structural organization and functionality of in vivo organ counterparts, offering significant potential for biomedical research and applications.

Current projects within the lab investigate inner ear neurodevelopmental disorders, explore the genetic and epigenetic mechanisms of human inner ear development, and seek to identify novel chemical compounds that could regenerate sensory hair cells. Utilizing CRISPR Cas9 genome technology, the lab is generating organoids and reporter stem cell lines to enhance the understanding and treatment of inner ear conditions.

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