Staley Lab

The Staley Lab at the University of Chicago specializes in unraveling the complexities of the spliceosome, the critical catalyst for nuclear pre-mRNA splicing, through various advanced genetic, biochemical, and biophysical techniques. Their pioneering research contributes to a deeper understanding of gene expression mechanisms and the regulatory functions of cellular processes and development.

With a focus on alternative splicing and fidelity in gene expression, the lab's innovative methods have led to significant discoveries, including insights into DEAH-box helicases and their roles in proofreading and catalyzing splicing. The team's collaborative environment fosters a dynamic approach to research, advancing knowledge in molecular biology and genetics.

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