Safeway

Mariano's Pharmacy in FRANKFORT, IL is staffed with professionals dedicated to helping you lead a healthier life. Protect yourself and your family with vaccinations, medicine and more. Our pharmacists do more than prepare prescription refills and dispense medical supplies; they also offer advice on health topics, perform clinical services, and administer vaccinations, including the Tdap vaccine, measles vaccine, shingles vaccine, flu shots and more. Need to request a prescription transfer or refill a medication? Our convenient online tools make it easy to manage your prescriptions quickly, simply and on your own schedule.

Looking for a grocery store near you? Visit your local Jewel-Osco located at 21164 S La Grange Rd, Frankfort, IL. Our friendly staff is here to serve you and your grocery needs, or have your groceries delivered through our Grocery Delivery and DriveUp & Go™ program. If you need immunizations or prescriptions refilled, Jewel-Osco pharmacy staff has you covered! Need a bakery near you? Our bakery features birthday cakes, custom cakes, cupcakes and more. Jewel-Osco deli offers a variety of party trays and platters or our Order Ahead service allows you to place your bakery or deli order online so it's ready when you get here! At the butcher block you’ll find an assortment of meat and seafood, even sushi trays! The produce department is full of guaranteed fresh fruits and vegetables, perfect for every season! Shop the floral department for beautifully curated bouquets and arrangements. Find Jewel-Osco near you today! Jewel-Osco is dedicated to being your one-stop-shop and provides rug doctor rentals or find an in-store bank, Coinstar, and Western Union service! Download our Jewel-Osco app for Jewel-Osco for U™ to find personalized offers and discounts or check out our Weekly Ad for store savings and earn Gas Points with purchases. For more information, visit or call (815) 464-5352. Stop by and see why our service, convenience, and fresh offerings will make Jewel-Osco your favorite local supermarket!