MaryLou B.
5/19/2025
I had an early morning appointment and I know traffic is crazy in the morning around Mayo Clinic. The hubby and I arrived early because we knew that Zest would offer us a delicious breakfast. I...
Zest at Mayo
$$
Closed
(37)
Photos
4500 San Pablo Rd S
Jacksonville, FL 32224
Zest at Mayo is a culinary venture created by local chefs and brothers Matthew and David Medure, located within the Mayo Building Atrium of the Jacksonville Mayo Clinic. This family-owned establishment offers a diverse menu featuring breakfast, lunch, and dinner, along with a convenient grab-and-go market for fresh salads, sandwiches, and protein bowls.
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Reviews
4.037 reviews
Kelly B.
8/20/2024
Service with a smile and ran like a well oiled machine. I don't know whose mama makes these grits but wow! So thick, creamy and yummy! They do need salt and pepper but don't need butter. This...
Kris F.
4/21/2024
A great little place to grab a quick bite if you're at Mayo Clinic for any reason. This is a Medure Brothers Grab N Go cafe! Everything they make here is tasty and fresh. You will not be...
Carl B.
8/22/2025
Hot breakfast combo was served with warm eggs, cold sausage & hash brown, cold hard biscuits. if you're going to sell a hot breakfast it should be served that way. I can't remember the last time I...
B D.
6/30/2025
Got the three cheese Italian grilled cheese. Great sandwich. Staff nice very nice. Came back for another one
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