Five Sisters Blues Cafe

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421 W Belmont St
Pensacola, FL 32501
Five Sisters' Blues Café, located at 421 West Belmont on the corner of Belmont and DeVilliers streets, is a restaurant built on some of Pensacola’s deepest history right in the heart of historic downtown Pensacola – The Blocks. For decades this intersection was the epicenter of African-American business and social life. It was here that the progression of musical culture made its mark in Pensacola Each of the four corners of the intersection feature buildings that date to the neighborhood’s historic period that served as the hub of the blues community; including Gussie’s Record Shop, WBOP Radio Station and Abe’s 506 Club. As talent passed through and the good times rolled, the neighborhood welcomed musicians Louis Armstrong, Aretha Franklin, Ike & Tina Turner, James Brown, Clarence Carter, Ray Charles, Fats Domino, Percy Sledge, Count Bassie, Wally Mercer Jr, Gwen McRae, Don Shirley, James & Bobby Purify and many, many more. In 2010, community leaders and active residents

Reviews

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4.0967 reviews
Photo of Domonique O.
Domonique O.
7/5/2025

Went down south to visit family and was flight was delayed until the next day. Decided to do some research on top eats in the area. All pointed to Five Sisters Blues Cafe for an amazing Southern...

Photo of Vivian P.
Vivian P.
6/3/2025

If you're looking for Southern food in the Pensacola area, Five Sisters Blues Café is a great choice. The Bloody Mary--packed with a bold kick and topped with a chicken wing that takes it to...

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Lady C.
5/23/2025

Mood: Early Lunch with Soul Love this downtown area and first time here after hearing great things. Service was a little short staffed but very sweet & working overtime. I enjoy the laid back...

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Madyson C.
7/2/2025

My friends and I stopped in on Monday to get the meatloaf special, unfortunately after we ordered we were informed they were out. Major disappointment. But our server was great and apologetic. We...

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Martita C.
8/22/2025

My husband and I were looking for some good fried chicken and heard that Five sisters have the best fried chicken in town. I ordered the 14 hour slow smoked beef brisket with sautéed mushrooms,...

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