Serrano's Pizza

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3274 21st St
San Francisco, CA 94110
Welcome to Serrano's Pizza, the best pizza in the Mission District in San Francisco! Located off of Lexington Street and 21st Street, we offer the best pizza by the slice and calzones around. Our lunch Slice Special comes with salad and a drink, and our reviews speak for themselves! We are a few blocks West of the City College of San Francisco. No frills here, just great pizza.

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Reviews

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3.5689 reviews
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Brandi H.
7/26/2025

We just happened to be parked infront of Serrano's so we thought why not get a late night snack. I've never heard or seen this spot but there seemed to be a steady flow of customers. We got a...

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Vic P.
1/14/2025

This review is more for the wings than anything else. I love that their serving of a slice of pizza is equivalent to TWO of the standard pizza shop's single slice serving size. Spectacular bc I...

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Jasmine Y.
9/22/2024

Note that I did not try their pizza but their pasta since I was craving that. Perhaps that was my mistake since it's Serrano's Pizza, not Serrano's Pasta. It came with garlic bread, which was...

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EL D.
6/27/2025

Ordered a slice of pepperoni and apparently it's made to order slices. After waiting a bit I received a huge personal slice pizza. Nice, hot and tasty. Here's the kicker...only $8.00!

Nerp D.
2/21/2025

Serranos Pizza is one of the best establishments and, perhaps, a once best kept secret among those that lived in the Mission District throughout the late 1990s, and the early aughts (you know,...

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