Serrano's Pizza

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3274 21st St
San Francisco, CA 94110
Welcome to Serrano's Pizza, the best pizza in the Mission District in San Francisco! Located off of Lexington Street and 21st Street, we offer the best pizza by the slice and calzones around. Our lunch Slice Special comes with salad and a drink, and our reviews speak for themselves! We are a few blocks West of the City College of San Francisco. No frills here, just great pizza.

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Reviews

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3.5692 reviews
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William B.
9/20/2025

When U Mention What Is My All Time Favorite Food Of All Time For Me That Would Be P-ì-ź-ź-ą & I Have Visited A Whole Bunch Of Pizza Locations All Over The States & Also Ate Pizza On A Cruise...

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Brandi H.
7/26/2025

We just happened to be parked infront of Serrano's so we thought why not get a late night snack. I've never heard or seen this spot but there seemed to be a steady flow of customers. We got a...

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Becca H.
11/17/2025

This spot is not bad for pizza. I am from NJ so unfortunately I am biased. I think it is decent if you are craving a slice of pizza, but the crust could be better. It is definitely a good spot for...

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Vic P.
1/14/2025

This review is more for the wings than anything else. I love that their serving of a slice of pizza is equivalent to TWO of the standard pizza shop's single slice serving size. Spectacular bc I...

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Jasmine Y.
9/22/2024

Note that I did not try their pizza but their pasta since I was craving that. Perhaps that was my mistake since it's Serrano's Pizza, not Serrano's Pasta. It came with garlic bread, which was...

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