One Main Cafe & Grill

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1303 E Herndon Ave
Fresno, CA 93720

Saint Agnes Medical Center in Fresno, CA offers a variety of dining options for visitors and staff, including One Main Cafe & Grill and Cyber Cafe. One Main Cafe Grill serves made-to-order omelets, sandwiches, sauteed selections, Angus beef burgers, gourmet pizzas, and healthy food choices, while Cyber Cafe offers Starbucks coffee, specialty sandwiches, salads, desserts, and snacks.

Visitors can enjoy a wide range of fresh selections at both dining areas, with the convenience of online ordering available at One Main Cafe Grill. The cafes provide a welcoming environment for guests to relax and enjoy delicious meals and beverages during their visit to the medical center.

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Reviews

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4.012 reviews
Beverly A.
4/13/2025

They had the best pozole in town. Only on Thursdays. The staff is the best!! They're always open and everything the make is amazing.

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Ashley L.
7/20/2025

7/19/25 It's in St. Agnes Hospital. Definitely a large hospital! Greeted upon entering the 2nd floor and that worker was great! Happy to give me a sticker pass to wear. I was looking for the...

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Michael V.
2/24/2023

Got lunch from the grill. Ordered the Classic Burger and Onion rings. The service was fast and the food was very good. The food is reasonably priced and they do not cook it until you put in...

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Susana M.
11/18/2019

I'm here at St. Agnes because my husband is in the hospital. I went downstairs to the Main Cafeteria to get something to eat. There are few choices for people who want to eat healthy and/or need...

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Daniel S.
9/20/2018

If you just need to eat something you can recognize. This is the place for you. Reasonably price OK service. You get what you pay for, and nothing more.

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United StatesCaliforniaFresnoOne Main Cafe & Grill

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