Lixte Biotechnology Holdings, Inc

Duet Biotherapeutics Inc. is an innovative immuno-oncology company based in Pasadena, California, dedicated to developing targeted immunotherapies for treatment-resistant cancers. Their unique approach focuses on creating bifunctional and cell-selective oligonucleotide treatments that activate dormant immune cells within the tumor microenvironment to enhance T cell-mediated immune responses against cancer cells. The company's therapeutic strategy centers on the simultaneous targeting of two key immune pathways, signal transducer and activator of transcription 3 (STAT3) and toll-like receptor 9 (TLR9). This dual pathway modulation has shown promising preclinical results, indicating significant potential for treating a range of malignancies, including aggressive solid tumors and blood cancers. Generated from the website

AcuraStem Inc., based in Pasadena, CA, is a pioneering biotechnology company focused on developing innovative treatments for neurodegenerative diseases, including sporadic ALS and FTD. Utilizing their proprietary disease-modeling platform, iNeuroRx, AcuraStem emphasizes a patient-based approach that leads to more effective and broadly applicable therapeutic solutions by generating individual patient models that accurately mimic disease processes. With a commitment to advancing drug development, AcuraStem has made significant strides in the field, as demonstrated by recent presentations from their leadership at prominent research summits. Their work aims to address the limitations of traditional animal models, fostering a deeper understanding of the human mechanisms that drive neurodegenerative diseases. Generated from the website

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