Cleave Bio

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866 Malcolm Rd
Burlingame, CA 94010
+1 (650) 443-3000
https://www.cleavebio.com

Cleave Biosciences is a biopharmaceutical company focused on developing novel therapeutics that target protein degradation pathways for challenging cancers. Their lead drug candidate, CB-5083, is a potent oral inhibitor of p97, a critical enzyme involved in protein homeostasis, currently undergoing Phase 1 clinical trials for multiple myeloma and advanced solid tumors.

The company's research emphasizes the role of AAA ATPases in cancer biology, aiming to identify new drug candidates that leverage a differentiated mechanism of action. With an extensive pipeline, Cleave Biosciences is dedicated to precision medicine approaches for patients with difficult-to-treat malignancies.

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