CERo Therapeutics Holdings, Inc

Novome Biotechnologies is a South San Francisco-based company that specializes in engineering living medicines for chronic diseases. Their innovative approach involves building cell therapies that are precise, extensible, and symbiotic with the patient, aiming to achieve long-term health. Novome's platform, GEMMs (Genetically Engineered Microbial Medicines), focuses on colonizing the gut with engineered microbes to deliver targeted therapeutic activities for sustained and effective treatments. With a strong emphasis on well-defined mechanisms of action and tunable treatment, Novome's therapies utilize highly-abundant gut microbes that are programmed with specific therapeutic functions. Their approach allows for convenient delivery through small, oral doses of a universal strain, making treatment safe, non-invasive, and tailored to specific conditions. Through their pipeline of programs, Novome aims to address a variety of diseases with clear etiology, including enteric hyperoxaluria, irritable bowel syndrome, and immuno-oncology.Generated from the website

SonoThera Inc., located in South San Francisco, is pioneering an ultrasound-mediated nonviral gene therapy platform aimed at delivering next-generation genetic medicines to various human organs. Their innovative technology seeks to address significant challenges in gene therapy, including safety, efficacy, biodistribution, and cost-effectiveness. With a focus on sonoporation, which has shown success in both preclinical and clinical settings, SonoThera is uniquely positioned to develop advanced gene therapies. The company's team is dedicated to building the future of gene therapy, leveraging their expertise to unlock the potential of genetic medicine. Generated from the website

Walking Fish Therapeutics is developing a platform to harness B cells' capability to activate the immune system in the treatment of cancer, and to serve as in vivo protein factories that produce replacement proteins for deficiency diseases, regenerative proteins, and engineered antibodies.