Elizabeth P.
10/19/2025
We ordered from the specials: short ribs and the mole enchiladas. Both were outstanding. Nice ambiance on a Sunday evening with live music. Lots of interesting decor. This place seems really...
The Guadalupe on Main
$$
Open
(221)
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1526 E Main St
Mesa, AZ 85203
The Guadalupe on Main in Mesa, AZ, offers a craft kitchen and cocktail experience on Main Street. Specializing in flavors from Jalisco, the restaurant provides a gluten-free friendly Mexican menu, inviting guests to savor authentic dishes.
With a focus on quality ingredients and innovative recipes, The Guadalupe on Main aims to create a unique dining experience for patrons seeking a taste of traditional Mexican cuisine with a modern twist.
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Reviews
4.5221 reviews
Michelle S.
11/8/2025
Guadeloupe on Main delivered a standout family-run dining experience. Our server, who also happened to be the chef's brother, set the tone immediately with warm, genuine hospitality that matched...
Andrea W.
10/31/2025
Gluten free eater here. This is really good Mexican food. Most places I have to pick and chose what I eat because of my gluten intolerance. Most everything on this menu is gluten free (except the...
Cheyenne J.
10/29/2025
Overall? It's fine, there are some great dishes and some not so great dishes. Service is meh. Ambiance is odd but the drinks are unique and tasty. So let's get into it.. The service was lacking...
Lenore B.
10/11/2025
Tucked just off the light rail and a quick hop from downtown Mesa, The Guad on Main feels like you've stumbled into your coolest friend's house if your friend also happened to be an artist, chef,...
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