Benjamin H.
8/28/2025
Wow such a great spot - been wanting to try this place forever now and finally caved this afternoon. Everything from the atmosphere service and food was perfect. Planning on coming back once a...
La Santisima
$$
Closed
(2,661)
Photos
4117 N 16th St
Phoenix, AZ 85016
Here at La Santisima, we aim to deliver everything that is exciting and fresh about Mexican cuisine to the people of Arizona. Our food combines fresh local produce from farms with unique flavors of chipotle chiles, bright green tomatillos, soft Oaxacan cheese, and pillowy flour and corn tortillas from Mexico. Located on 16th street, just North of McDowell, our menu features gourmet tacos, quesas, burritos, seafood, and a fantastic salsa bar filled with homemade salsas. Try our fruit infused horchata and enjoy beer and margaritas from the bar. Stop by for lunch or dinner today!
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Reviews
4.02,661 reviews
Jon H.
8/2/2025
Was out in Phoenix and my friend bet their life on how great La Santisima was...so we had to go. Not gonna lie, it was pretty fantastic! The decor and art in the place was amazing, loved it! They...
Daniel R.
5/30/2025
Mexican food so good that I want to move to Phoenix! Visiting from Southern California, I was curious to see how Phoenix mexican food compares and I was absolutely impressed. Approaching the...
Andrew L.
9/1/2025
Fully stoked I finally tried this place on a trip to phoenix. Probably the best fish taco I've ever had. Everything was really great. The art and ambiance were spectacular! And my server was busy...
Catherine H.
5/15/2025
La Santisima. This is one of the top two places I send people when they ask about good Mexican. When my husband and I first moved in together some 14 years ago, this place was called La Condesa,...
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