Belsham Lab

The Belsham Laboratory at the University of Toronto is dedicated to exploring the molecular mechanisms underlying the diverse physiological functions of the hypothalamus, particularly in relation to growth, reproduction, nutrition, sleep, and stress responses. The lab focuses on the roles of neuropeptides and neurotransmitters, notably gonadotropin-releasing hormone (GnRH), and the impact of various internal and external stimuli on the hypothalamic neurons that regulate these vital processes.

In addition to studying reproductive functions, the Belsham Lab investigates neuropeptides involved in energy homeostasis, analyzing gene expression and signal transduction in response to peripheral signals such as insulin and glucagon. This research aims to elucidate the intricate connections between nutritional status and reproduction, enhancing the understanding of integrated neuroendocrine control within basic physiology.

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