Carolyn Brown

2350 Health Sciences Mall
Vancouver, BC V6T 1Z3

The University of British Columbia's Department of Medical Genetics, led by Professor Carolyn J. Brown, focuses on advancing the understanding of X-chromosome inactivation and its clinical implications for female mammals. Through innovative research, the department investigates the underlying mechanisms of gene silencing, particularly the role of long non-coding RNAs, and their contribution to gene expression differences between genders.

Dr. Brown's lab employs cutting-edge techniques, exploring both the establishment and maintenance of X-chromosome inactivation as well as how certain genes evade silencing. Collaborating with notable institutions, they aim to uncover insights into epigenetic regulation and its impact on health, ultimately enhancing the understanding of conditions associated with X-chromosome aneuploidies.

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